Concepedia

Novel long noncoding RNA OTUD6B-AS1 indicates poor prognosis and inhibits clear cell renal cell carcinoma proliferation via the Wnt/β-catenin signaling pathway

Gang Wang, Zijian Zhang, Wengang Jian, Panhong Liu, Wei Xue, Tengda Wang, Yuyang Meng, Chao Yuan, Hao-Ming Li, Yipeng Yu,

Molecular Cancer · 2019 · 166 citations · 34 references

DOIFull text

Open access

Abstract

Taken together, our findings present a road map for targeting the newly identified lncRNA OTUD6B-AS1 to suppress ccRCC progression in cell lines, and these results elucidate a novel potential therapeutic target for ccRCC treatment.

References

34

Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer

Xiang-hua Liu, Ming Sun, Feng-qi Nie et al. · Molecular Cancer · 2014 · 984 citations · Full text

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal

Samra Turajlic, Hang Xu, Kevin Litchfield et al. · Cell · 2018 · 835 citations · Full text

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lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

Yuanyuan Lu, Xiaodi Zhao, Qi Liu et al. · Nature Medicine · 2017 · 448 citations · Full text

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LINC01133 as ceRNA inhibits gastric cancer progression by sponging miR-106a-3p to regulate APC expression and the Wnt/β-catenin pathway

Xianzi Yang, Tiantian Cheng, Qingjun He et al. · Molecular Cancer · 2018 · 400 citations · Full text

LncRNA loc285194 is a p53-regulated tumor suppressor

Qian Liu, Jianguo Huang, Nanjiang Zhou et al. · Nucleic Acids Research · 2013 · 398 citations · Full text