Hydrazones as novel epigenetic modulators: Correlation between TET 1 protein inhibition activity and their iron(II) binding ability

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

Kathryn Blaschke, Kevin Ebata, Mohammad M. Karimi et al. · Nature · 2013 · 882 citations

Life Sciences, Genetics, Molecular Biology +15

<i>TET1</i> plays an essential oncogenic role in <i>MLL</i> -rearranged leukemia

Hao Huang, Xi Jiang, Zejuan Li et al. · Proceedings of the National Academy of Sciences · 2013 · 223 citations · Full text

Life Sciences, Genetics, Oncology +17

Future of ToxicologyIron Chelators and Differing Modes of Action and Toxicity:  The Changing Face of Iron Chelation Therapy

Danuta S. Kalinowski, Des R. Richardson · Chemical Research in Toxicology · 2007 · 146 citations

Medicine, Pharmacology, Toxicology +14

A genome‐wide profiling of brain DNA hydroxymethylation in Alzheimer's disease

Jinying Zhao, Yun Zhu, Jingyun Yang et al. · Alzheimer s & Dementia · 2017 · 110 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells

Sujan Badal, Yeng F. Her, L. James Maher · Journal of Biological Chemistry · 2015 · 108 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9