Nanoscale Horizons · 2019 · 103 citations · 40 references
Life SciencesBiotechnologyPharmaceuticsBiosensorsDrug DeliveryCell-nanoparticle InteractionsCell-surface ReceptorsNanomaterial-based BiosensorsNanomedicineNanoparticle DesignTargeting LigandsMolecularly Imprinted MaterialsNanoparticle-based BiosensorsNanoparticle-based ProbesProtein Surface ImmobilizationSenescent Cell Accumulation
Nanoparticles (MIPs) specifically detect and target senescent cells by binding to a surface protein, showing also specificity<italic>in vivo</italic>.
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Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text
Medicine, Cell Biology, Oncology +10
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Darren J. Baker, Tobias Wijshake, Tamar Tchkonia et al. · Nature · 2011 · 3.6K citations · Full text
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
Darren J. Baker, Bennett G. Childs, Matej Durik et al. · Nature · 2016 · 2.8K citations · Full text
BRAFE600-associated senescence-like cell cycle arrest of human naevi
Chrysiis Michaloglou, Liesbeth C.W. Vredeveld, Marı́a S. Soengas et al. · Nature · 2005 · 2.1K citations · Full text
Life Sciences, Biology, Cell Biology +12