Concepedia

Nrf2 deficiency exacerbates frailty and sarcopenia by impairing skeletal muscle mitochondrial biogenesis and dynamics in an age-dependent manner

Dongdong Huang, Sheng-Dong Fan, Xiyi Chen, Xialin Yan, Xian-Zhong Zhang, Bingwei Ma, Dingye Yu, Wenyu Xiao, Cheng‐Le Zhuang, Zhen Yu

Experimental Gerontology · 2019 · 158 citations · 29 references

DOI

Concepts

References

29

Frailty in Older Adults: Evidence for a Phenotype

Linda P. Fried, Catherine M. Tangen, Jeremy Walston et al. · The Journals of Gerontology Series A · 2001 · 24.5K citations · Full text

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Sarcopenia: European consensus on definition and diagnosis

Alfonso J. Cruz‐Jentoft, Jean‐Pierre Baeyens, Jürgen M. Bauer et al. · Age and Ageing · 2010 · 11.7K citations · Full text

, , +17

Accumulation of Deficits as a Proxy Measure of Aging

Arnold B. Mitnitski, Alexander Mogilner, Kenneth Rockwood · The Scientific World JOURNAL · 2001 · 2.9K citations · Full text

, , +16

Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

Gregory C. Kujoth, Asimina Hiona, Thomas D. Pugh et al. · Science · 2005 · 2.2K citations

, , +17

Inflammatory Markers and Loss of Muscle Mass (Sarcopenia) and Strength

L. Schaap, Saskia M.F. Pluijm, Dorly J. H. Deeg et al. · The American Journal of Medicine · 2006 · 1K citations

, , +14