Concepedia

Early Administration of Antibiotics for Suspected Sepsis

Michael Mi, Michael Klompas, Laura Evans

New England Journal of Medicine · 2019 · 46 citations · 13 references

DOI

Concepts

Abstract

This interactive feature about early administration of antibiotics in patients with suspected sepsis offers case vignettes accompanied by essays that support either recommending or discouraging the use of antibiotics in such patients. Vote and comment at NEJM.org.

References

13

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Mervyn Singer, Clifford S. Deutschman, Christopher W. Seymour et al. · JAMA · 2016 · 28K citations · Full text

, , +17

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*

Anand Kumar, Daniel Roberts, Kenneth E. Wood et al. · Critical Care Medicine · 2006 · 6.1K citations

, , +13

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

Andrew Rhodes, Laura Evans, Waleed Alhazzani et al. · Critical Care Medicine · 2017 · 3.8K citations · Full text

, , +16

Assessment of Clinical Criteria for Sepsis

Christopher W. Seymour, Theodore J. Iwashyna, Frank M. Brunkhorst et al. · JAMA · 2016 · 3.8K citations · Full text

, , +17

Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America

Tamar F. Barlam, Sara E. Cosgrove, Lilian M. Abbo et al. · Clinical Infectious Diseases · 2016 · 3K citations · Full text

, , +17