Annals of Gastroenterology and the Digestive System · 2018 · 35 citations · 29 references
MedicineInternal MedicinePharmacotherapyGastroenterologyHemodynamic ManagementHemostasisAcute Gastrointestinal HemorrhageGastrointestinal BleedingGastrointestinal Bleeding ManagementAcute Hemorrhage Severity ScoringAcute Upper Gastrointestinal BleedingAnnual IncidenceClinical Risk ScoresEsophageal Variceal HemorrhageHemorrhage Severity AssessmentRisk Stratification ScoresVariceal Bleeding Management
The purpose of this review is to summarize the management of upper gastrointestinal bleeding (UGIB). This entity has an annual incidence of 48 to 160 cases per 100,000 adults, with a mortality rate of 10% to 14%. Classically, UGIB is divided in non-variceal hemorrhage and variceal hemorrhage, being more frequently observed the first one (80%-90%). The initial management includes investigate about the form of presentation, color and characteristics of the hemorrhage, the age of the patient, presence of coagulopathy, disease or cardiovascular risk factors, use of nonsteroidal anti-inflammatory drugs (NSAIDs), antiaggregants or anticoagulants, previous episodes of hemorrhage, endoscopy, alcohol intake, etc. However, this process must not delay the initiation of hemodynamic resuscitation in patients with patients with ongoing bleeding. To stratify these patients, risk scores including Blatchford score and Rockall score are developed.
29
Transfusion Strategies for Acute Upper Gastrointestinal Bleeding
Càndid Villanueva, Alan Colomo, Alba Fernández Bosch et al. · New England Journal of Medicine · 2013 · 1.7K citations · Full text
Medicine, Hematology, Hemostasis +12
Risk assessment after acute upper gastrointestinal haemorrhage.
Timothy Rockall, Richard F. Logan, Hugh Devlin et al. · Gut · 1996 · 1.5K citations · Full text
Veterinary Medicine, Geriatric Medicine, Clinical Epidemiology +16
Clopidogrel with or without Omeprazole in Coronary Artery Disease
Deepak L. Bhatt, Byron Cryer, Charles F. Contant et al. · New England Journal of Medicine · 2010 · 1.2K citations · Full text