Acylated flavonoid glycosides from <i>Barringtonia racemosa</i>

Abstract

Using various chromatographic separations, three new acylated flavonoid glycosides, namely barringosides G-I (<b>1</b>-<b>3</b>), were isolated from the water-soluble extract of <i>Barringtonia racemosa</i> branches and leaves. The structure elucidation was performed by extensive analysis of the 1D and 2D NMR and HR-QTOF-MS data. Of the isolated compounds, barringoside I (<b>3</b>) showed moderate inhibitory effects on LPS-induced NO production in RAW264.7 cells with an IC₅₀ of 52.48 ± 1.04 µM.