Itraconazole Induces Regression of Infantile Hemangioma via Downregulation of the Platelet-Derived Growth Factor–D/PI3K/Akt/mTOR Pathway

Growth Characteristics of Infantile Hemangiomas: Implications for Management

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Medicine, Dermatology, Pediatrics +17

Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

Mindaugas Valius, Andrius Kazlauskas · Cell · 1993 · 657 citations

Life Sciences, Biochemistry, Cell Biology +17

Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation

Bin Zheng, Joseph H. Jeong, John M. Asara et al. · Molecular Cell · 2009 · 354 citations · Full text

Medicine, Cancer Biology, Oncology +16

Open-Label, Exploratory Phase II Trial of Oral Itraconazole for the Treatment of Basal Cell Carcinoma

Daniel J. Kim, James Kim, Katrina Spaunhurst et al. · Journal of Clinical Oncology · 2014 · 285 citations · Full text

Medicine, Oncology, Pharmacology +14

Genetic mapping of a novel familial form of infantile hemangioma

Jeffrey W. Walter, Francine Blei, Jennifer Anderson et al. · American Journal of Medical Genetics · 1999 · 174 citations

Life Sciences, Genetics, Pathology +14