Natural Product Research · 2019 · 10 citations · 14 references
Life SciencesMedicinal ChemistryPharmacologyDrug DiscoveryEthnobotanyPlant BiochemistryAnthelmintic PharmacologyCholinergic NeurochemistryCholinergic PharmacologyMedicinal Plant KnowledgeMedicinal PlantsStructure-activity Relationship AnalysisMedicinal HerbsPlant AlkaloidsTraditional Herbal Medicine
A new C19-diterpenoid alkaloid named hemsleyaline (1), along with fourteen known alkaloids (2-15), were isolated from the roots of Aconitum hemsleyanum Pritz. (Ranunculaceae), a herbal medicine in southwest China. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 showed mild cholinesterase inhibitory effect with IC50 value of 471 ± 9 μM.
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Diterpenoid alkaloids from Aconitum vilmorinianum
Tianpeng Yin, Le Cai, Haixian Fang et al. · Phytochemistry · 2015 · 54 citations