Inhibition of tumor necrosis factor-alpha (TNF-alpha) in patients with early rheumatoid arthritis results in acute changes of bone modulators

Dickkopf-1 is a master regulator of joint remodeling

Danielle Diarra, Marina Stolina, Karin Polzer et al. · Nature Medicine · 2007 · 1.3K citations

Medicine, Molecular Genetics, Orthopedic Surgery +4

Circulating Dickkopf-1 Is Correlated with Bone Erosion and Inflammation in Rheumatoid Arthritis

Shiyao Wang, Yanying Liu, Hua Ye et al. · The Journal of Rheumatology · 2011 · 150 citations · Full text

Medicine, Immunology, Internal Medicine +17

Certolizumab pegol in combination with dose-optimised methotrexate in DMARD-naïve patients with early, active rheumatoid arthritis with poor prognostic factors: 1-year results from C-EARLY, a randomised, double-blind, placebo-controlled phase III study

Paul Emery, Clifton O. Bingham, Gerd R Burmester et al. · Annals of the Rheumatic Diseases · 2016 · 100 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

In patients with rheumatoid arthritis, Dickkopf-1 serum levels are correlated with parathyroid hormone, bone erosions and bone mineral density.

Maurizio Rossini, Ombretta Viapiana, Silvano Adami et al. · PubMed · 2015 · 80 citations

Medicine, Endocrinology, Internal Medicine +15

Reliability and sensitivity to change of the Simple Erosion Narrowing Score compared with the Sharp–van der Heijde method for scoring radiographs in rheumatoid arthritis

Eufemia Dias, C. Lukas, Robert Landewé et al. · Annals of the Rheumatic Diseases · 2007 · 62 citations

Medicine, Clinical Sciences, Internal Medicine +17