Concepedia

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay

Jerzy M. Dziekan, Han Yu, Dan Chen, Lingyun Dai, Grennady Wirjanata, Andreas Larsson, Nayana Prabhu, Radoslaw M. Sobota, Zbynek Bozdech, P. Nordlund

Science Translational Medicine · 2019 · 231 citations · 62 references

DOI

Concepts

Abstract

constitutes a promising strategy to elucidate the MoAs of existing and candidate antimalarial drugs.

References

62

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan · Acta Crystallographica Section D Biological Crystallography · 2004 · 31.4K citations · Full text

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<i>Phaser</i>crystallographic software

Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al. · Journal of Applied Crystallography · 2007 · 20.9K citations · Full text

, , +16

<i>XDS</i>

Wolfgang Kabsch · Acta Crystallographica Section D Biological Crystallography · 2010 · 16.9K citations · Full text

, , +13

<i>REFMAC</i>5 for the refinement of macromolecular crystal structures

Garib N. Murshudov, Pavol Skubák, Andrey A. Lebedev et al. · Acta Crystallographica Section D Biological Crystallography · 2011 · 8.7K citations · Full text

, , +17

Genome sequence of the human malaria parasite Plasmodium falciparum

Malcolm J. Gardner, Neil Hall, Eula Fung et al. · Nature · 2002 · 4.5K citations · Full text

, , +13