Nitric oxide protected against NADPH oxidase-derived superoxide generation in vascular endothelium: Critical role for heme oxygenase-1

Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase.

Robert M. Clancy, J Leszczynska-Piziak, Steven B. Abramson · Journal of Clinical Investigation · 1992 · 693 citations · Full text

Inflammation, Intact Neutrophils, Redox Signaling +15

NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium

Roberto Motterlini, Roberta Foresti, Marcos Intaglietta et al. · American Journal of Physiology-Heart and Circulatory Physiology · 1996 · 314 citations

Endothelial Cells, Nitric Oxide, Cell Death +19

Nitric oxide suppresses NADPH oxidase-dependent superoxide production by S-nitrosylation in human endothelial cells

Stavros Selemidis, G. J. Dusting, Hitesh Peshavariya et al. · Cardiovascular Research · 2007 · 216 citations · Full text

Induction of Heme Oxygenase-1 In Vivo Suppresses NADPH Oxidase–Derived Oxidative Stress

Srinivasa Raju Datla, Gregory J. Dusting, Trevor A. Mori et al. · Hypertension · 2007 · 192 citations · Full text

Heme Oxygenase-1, Nadph Oxidase Activity, Redox Biology +18

Induction of Heme Oxygenase-1 Inhibits NAD(P)H Oxidase Activity by Down-regulating Cytochrome b558 Expression via the Reduction of Heme Availability

Camille Taillé, Jamel El‐Benna, Sophie Lanone et al. · Journal of Biological Chemistry · 2004 · 179 citations · Full text