Concepedia

Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold

Shaimaa S. Goher, Kristine Griffett, Lamees Hegazy, Mohamed Elagawany, M. M. H. Arief, Amer Avdagic, Subhashis Banerjee, Thomas P. Burris, Bahaa Elgendy

Bioorganic & Medicinal Chemistry Letters · 2018 · 22 citations · 14 references

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14

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

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Safety, Pharmacokinetics, and Pharmacodynamics of Single Doses of LXR‐623, a Novel Liver X‐Receptor Agonist, in Healthy Participants

Arie Katz, Chandrasekhar Udata, Elyssa Ott et al. · The Journal of Clinical Pharmacology · 2009 · 206 citations

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Broad-Spectrum Therapeutic Suppression of Metastatic Melanoma through Nuclear Hormone Receptor Activation

Nora Pencheva, Colin G. Buss, Jessica M. Posada et al. · Cell · 2014 · 171 citations · Full text

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A Liver-Selective LXR Inverse Agonist That Suppresses Hepatic Steatosis

Kristine Griffett, Laura A. Solt, Theodore M. Kamenecka et al. · ACS Chemical Biology · 2012 · 122 citations

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A base-catalyzed, direct synthesis of 3,5-disubstituted 1,2,4-triazoles from nitriles and hydrazides

Kap‐Sun Yeung, Michelle E. Farkas, John F. Kadow et al. · Tetrahedron Letters · 2005 · 92 citations

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