Kaempferol attenuates retinal ganglion cell death by suppressing NLRP1/NLRP3 inflammasomes and caspase-8 via JNK and NF-κB pathways in acute glaucoma

Global data on visual impairment in the year 2002.

Serge Resnikoff, Donatella Pascolini, Daniel Etya’ale et al. · PubMed · 2004 · 4.2K citations

Medicine, Ophthalmology, Global Health +16

Retinal Ganglion Cell Apoptosis in Glaucoma Is Related to Intraocular Pressure and IOP-Induced Effects on Extracellular Matrix

Li Guo, Stephen E. Moss, Robert Alexander et al. · Investigative Ophthalmology & Visual Science · 2004 · 351 citations · Full text

Medicine, Cell Biology, Ophthalmology +15

Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1β production in acute glaucoma

Wei Chi, Fei Li, Hongrui Chen et al. · Proceedings of the National Academy of Sciences · 2014 · 313 citations · Full text

Life Sciences, Ophthalmology, Pathobiology +17

HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma

Wei Chi, Hongrui Chen, Fei Li et al. · Journal of Neuroinflammation · 2015 · 208 citations · Full text

Life Sciences, Ophthalmology, Pathobiology +17

Kaempferol regulates MAPKs and NF-κB signaling pathways to attenuate LPS-induced acute lung injury in mice

Xiaojun Chen, Xiaofeng Yang, Tianjiao Liu et al. · International Immunopharmacology · 2012 · 178 citations

Life Sciences, Immunology, Pharmacology +12