Concepedia

Disruption of the ZBED6 binding site in intron 3 of IGF2 by CRISPR/Cas9 leads to enhanced muscle development in Liang Guang Small Spotted pigs

Xiaofeng Liu, Hongbo Liu, Min Wang, Ruiqiang Li, Jianhua Zeng, Delin Mo, Peiqing Cong, Xiaohong Liu, Yaosheng Chen, Zuyong He

Transgenic Research · 2018 · 81 citations · 12 references

DOI

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References

12

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

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A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig

Anne-Sophie Van Laere, Minh Quang Nguyen, Martin Braunschweig et al. · Nature · 2003 · 963 citations

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Surrogate reporters for enrichment of cells with nuclease-induced mutations

Hyojin Kim, Jin‐Soo Kim · Nature Methods · 2011 · 209 citations · Full text

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Editing porcine IGF2 regulatory element improved meat production in Chinese Bama pigs

Guanghai Xiang, Jilong Ren, Tang Hai et al. · Cellular and Molecular Life Sciences · 2018 · 107 citations · Full text

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The ZBED6–IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals

Shady Younis, Milena Schönke, Julie Massart et al. · Proceedings of the National Academy of Sciences · 2018 · 99 citations · Full text

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