Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model

Spatial memory, recognition memory, and the hippocampus

Nicola Broadbent, Larry R. Squire, Robert E. Clark · Proceedings of the National Academy of Sciences · 2004 · 988 citations · Full text

Social Sciences, Neuroscience, Psychology +17

Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation

Hisae Kadowaki, Hideki Nishitoh, Fumihiko Urano et al. · Cell Death and Differentiation · 2004 · 429 citations · Full text

Life Sciences, Cell Biology, Neuroscience +16

Decreased Melatonin Levels in Postmortem Cerebrospinal Fluid in Relation to Aging, Alzheimer’s Disease, and Apolipoprotein E-ε4/4 Genotype¹

Rong‐Yu Liu, Jiang‐Ning Zhou, Joop van Heerikhuize et al. · The Journal of Clinical Endocrinology & Metabolism · 1999 · 306 citations · Full text

Medicine, Endocrinology, Neuroscience +17

BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

Masuo Ohno, Sarah L. Cole, Marina V. Yasvoina et al. · Neurobiology of Disease · 2006 · 292 citations · Full text

Life Sciences, Genetics, Neuroscience +14

Early neuropathological Alzheimer's changes in aged individuals are accompanied by decreased cerebrospinal fluid melatonin levels

Jiang‐Ning Zhou, Rong‐Yu Liu, Wouter Kamphorst et al. · Journal of Pineal Research · 2003 · 272 citations

Medicine, Neurology, Neuroscience +16