Evaluation of in-vitro cytotoxic effect of 5-FU loaded-chitosan nanoparticles against spheroid models.

Taylor Smith, Kevin Affram, Errol Bulumko, Edward Agyare

PubMed · 2018 · 26 citations · 24 references

Full text

Open access

Abstract

5-FUChnps were significantly cytotoxic to the 3D HCT-116 cultures than that of the free 5-FU. Chnps proved to have the ability to deliver and improve the anticancer activity of 5-FU in 3D HCT-116 culture studies.

References

24