Cancer Investigation · 2018 · 14 citations · 38 references
MedicineOncologyRadiation OncologyBreast OncologyClinical Radiation OncologyRadiation SafetyBreast Cancer RadiotherapyRadiation TherapyRadiation ToxicityRadiation Treatment PlanningToxicity GradingToxicity ManagementAcute Adverse EventsChest Wall ToxicityHelical TomotherapyLate Skin ToxicityPost-mastectomy RadiotherapyPostmastectomy Radiation TherapySerious Adverse EventsSkin Toxicity Grading
INTRODUCTION: To evaluate the incidence of toxicity in breast cancer with helical tomotherapy (HT). MATERIALS AND METHODS: 51 patients with breast cancer were assigned to postoperative radiotherapy by means of HT to the chest wall/breast plus draining nodes. During HT treatment, toxicity was monitored and were assessed using the Common Terminology Criteria for Adverse Events 4.0 scale. RESULTS: Acute skin G3 toxicity observed in 1.9% cases. No acute or late G4 toxicity was observed. At a median follow-up of 21 months 2 patients have late G1 toxicity. CONCLUSIONS: HT was associated with a low incidence of low-grade skin toxicity.
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