Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex

Abstract

(Cell 158, 1123–1135; August 28, 2014) In preparing the article above, we inadvertently assigned the coordinates for eIF3f to its homolog eIF3h and vice versa within the mammalian eIF3 model during PDB database deposition. This error led to improper positioning of these subunits in Figures 3E, 7F, and S2B. We present below revised panels for Figures 3 and 7 with the correct assignment for eIF3f and eIF3h. These figures, along with Figure S2, have been corrected online. The deposited PDB files have also been corrected and updated. In addition, we have added the missing legend for Figure S2B online. We apologize for any confusion that these errors may have caused.Figure 7Placement and Interactions of eIF3 Components on 40SView Large Image Figure ViewerDownload Hi-res image Download (PPT) Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation ComplexErzberger et al.CellAugust 28, 2014In BriefA hybrid approach drawing on X-ray structures, crosslinking coupled to mass spectrometry, electron microscopy, and integrative modeling yields mechanistic insights into how eIF3 coordinates translation initiation. Full-Text PDF Open Access