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Publication | Open Access

Glucose-Sensitive Myokine/Cardiokine MG53 Regulates Systemic Insulin Response and Metabolic Homeostasis

DOIFull Paper Access

120

Citations

37

References

2019

Year

Hongkun Wu, Yan Zhang, Chunmei Cao, Xinli Hu, Meng Fang, Yuan Yao, Jin Li, Gengjia Chen, Peng Jiang, Shuo Zhang,
Circulation

Abstract

Thus, MG53 has dual actions as a myokine/cardiokine and an E3 ligase, synergistically inhibiting the insulin signaling pathway. Targeting circulating MG53 opens a new therapeutic avenue for T2DM and its complications.

References

YearCitations

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