Understanding the mechanisms of cancers based on function sub-pathways

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

Life Sciences, Bioinformatics, Oncology +12

KEGG: Kyoto Encyclopedia of Genes and Genomes

Minoru Kanehisa · Nucleic Acids Research · 2000 · 39.2K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +5

KEGG: Kyoto Encyclopedia of Genes and Genomes

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PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Vamsi K. Mootha, Cecilia M. Lindgren, Karl‐Fredrik Eriksson et al. · Nature Genetics · 2003 · 10.6K citations

Life Sciences, Endocrinology, Molecular Biology +16

Reactome: a knowledgebase of biological pathways

Nucleic Acids Research · 2004 · 1.3K citations · Full text

Life Sciences, Bioinformatics, Biology +17