TSLP promotes asthmatic airway remodeling via p38-STAT3 signaling pathway in human lung fibroblast

Abstract

TSLP might promote asthmatic airway remodeling via p38 MAPK-STAT3 axis activation and the crosstalk between airway epithelial cells and fibroblasts could aggravate remodeling. Blockade of p38 could alleviate airway remodeling which might provide a new therapeutic target for asthma.