IR-A/IGF-1R-mediated signals promote epithelial-mesenchymal transition of endometrial carcinoma cells by activating PI3K/AKT and ERK pathways - Concepedia

Concepedia

Publication | Open Access

IR-A/IGF-1R-mediated signals promote epithelial-mesenchymal transition of endometrial carcinoma cells by activating PI3K/AKT and ERK pathways

DOI Full Paper Access

15

Citations

26

References

2018

Year

Chunfang Wang, Ke Su, Yanyan Zhang, Weiwei Zhang, Qian Zhao, Danxia Chu, Ruixia Guo

Cancer Biology & Therapy

Abstract

IR-A and IGF-1R-mediated signals, by activating PI3K/AKT and ERK pathways, can induce multiple malignant phenotypes of EC cells. Therefore, targeting IR-A or IGF-1R may provide therapeutic benefits for EC.

References

	Year	Citations

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