Oncogenic Amplification of Zygotic Dux Factors in Regenerating p53-Deficient Muscle Stem Cells Defines a Molecular Cancer Subtype

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

Medicine, Cancer Biology, Molecular Genetics +14

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

Ittai Ben‐Porath, Matthew Thomson, Vincent J. Carey et al. · Nature Genetics · 2008 · 2.6K citations · Full text

Life Sciences, Cancer Biology, Oncology +16

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Cristian Tomasetti, Bert Vogelstein · Science · 2015 · 2K citations

Medicine, Cancer Biology, Oncology +16

Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin

Katherine A. Hoadley, Christina Yau, Denise M. Wolf et al. · Cell · 2014 · 1.6K citations · Full text

Veterinary Medicine, Molecular Biology, Oncology +14

Integrated molecular analysis of clear-cell renal cell carcinoma

Yusuke Sato, Tetsuichi Yoshizato, Yuichi Shiraishi et al. · Nature Genetics · 2013 · 1.3K citations

Medicine, Molecular Biology, Oncology +13