The Journal of the American Board of Family Medicine · 2018 · 24 citations · 23 references
NursingGeriatric MedicineAddiction PsychiatryDrug Utilization ReviewSubstance Use DisordersDrug Overdose PreventionOpioid Use DisorderOverdose PreventionCohort Study InvestigationOpioid Risk AssessmentOpioid Use EpidemiologyPrimary Outcome Analysis
<h3>Introduction:</h3> As the opioid epidemic progresses, a better understanding of those at elevated risk of opioid overdose is needed, particularly for populations whose growing risk may be overlooked. Medicare recipients under age 65 (Medicare-disability beneficiaries [MDBs]) are one such population. We sought to analyze characteristics of opioid-overdose hospitalizations among MDBs and quantify the contribution of this population to opioid-overdose hospitalizations overall. <h3>Methods:</h3> This retrospective cohort study included patients hospitalized for opioid overdose in the National/Nationwide Inpatient Sample from 1998 to 2013. The primary outcome measurements were number and characteristics of discharges, including patient sex, age, race, prescription opioid versus heroin overdose, and comorbidities. <h3>Results:</h3> MDBs constituted 11.7% of US opioid overdose hospitalizations among those under 65 years of age in 1998; this proportion grew to 24.5% by 2013 (<i>P</i> < .0001). The proportion of female patients grew markedly among this cohort (<i>P</i> < .0001) and were disproportionately represented among MDBs (<i>P</i> < .0001). Prescription opioid overdose accounted for a larger proportion of opioid overdose hospitalizations among MDBs than among non-Medicare-insured patients under 65 years old (<i>P</i> < .0001). MDBs generally exhibited greater comorbidity burden versus non-Medicare-insured patients under age 65; however, chronic drug and alcohol abuse were less commonly documented among the Medicare cohort (<i>P</i> < .0001). <h3>Conclusions:</h3> MDBs constitute a substantial and growing proportion of opioid overdose hospitalizations in the United. To prevent opioid overdoses among MDBs, care must be taken to address the unique needs of this population.
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Increases in Drug and Opioid-Involved Overdose Deaths — United States, 2010–2015
Rose A. Rudd, Puja Seth, Felicita David et al. · MMWR Morbidity and Mortality Weekly Report · 2016 · 2.2K citations · Full text
Pharmacy, Pharmacology, Toxicology +16
Quantifying the Epidemic of Prescription Opioid Overdose Deaths
Puja Seth, Rose A. Rudd, Rita K. Noonan et al. · American Journal of Public Health · 2018 · 438 citations · Full text