Translation of Carbon‐13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients

Abstract

This study demonstrated the feasibility of symmetric EPI to acquire HP ¹³ C metabolite maps in a clinical setting. As an advance over prior single-slice dynamic or single time point volumetric spectroscopic imaging approaches, this metabolite-specific EPI acquisition provided robust whole-organ coverage for brain and prostate studies while retaining high SNR, spatial resolution, and dynamic temporal resolution.