Concepedia

MicroRNA-588 regulates invasion, migration and epithelial–mesenchymal transition via targeting EIF5A2 pathway in gastric cancer

Xiaorong Zhou, Manli Xu, Yonghong Guo, Ling Ye, Limin Long, Haiqin Wang, Pan Tan, Meili Xu

Cancer Management and Research · 2018 · 28 citations · 20 references

DOIFull text

Open access

Abstract

Overall, the findings of the study suggest that miR-588 acts as a tumor suppressor by regulating the invasion, migration and EMT via EIF5A2 pathway, hence presenting miR-588 as a prognostic marker as well as a therapeutic target for GC.

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