MicroRNA-588 regulates invasion, migration and epithelial–mesenchymal transition via targeting EIF5A2 pathway in gastric cancer - Concepedia

Concepedia

Publication | Open Access

MicroRNA-588 regulates invasion, migration and epithelial&ndash;mesenchymal transition via targeting EIF5A2 pathway in gastric cancer

DOI Full Paper Access

28

Citations

20

References

2018

Year

Xiaorong Zhou, Manli Xu, Yonghong Guo, Ling Ye, Limin Long, Haiqin Wang, Pan Tan, Meili Xu

Cancer Management and Research

Abstract

Overall, the findings of the study suggest that miR-588 acts as a tumor suppressor by regulating the invasion, migration and EMT via EIF5A2 pathway, hence presenting miR-588 as a prognostic marker as well as a therapeutic target for GC.

References

	Year	Citations
Cancer statistics, 2013 Rebecca L. Siegel, Deepa Naishadham, Ahmedin Jemal CA A Cancer Journal for Clinicians	2013	11.9K
MicroRNA expression profiles classify human cancers Jun Lü, Gad Getz, Eric A. Miska, Nature PathologyCancer GenomicsMicrorna Expression ProfilesMicrorna DetectionMedicine	2005	9.5K
Mammalian microRNAs predominantly act to decrease target mRNA levels Huili Guo, Nicholas T. Ingolia, Jonathan S. Weissman, Nature Mammalian MicrornasMicrorna DetectionSmall RnaGene ExpressionMedicine	2010	3.9K
Patterns of Cancer Incidence, Mortality, and Prevalence Across Five Continents: Defining Priorities to Reduce Cancer Disparities in Different Geographic Regions of the World Farin Kamangar, Graça M. Dores, William F. Anderson Journal of Clinical Oncology Epidemiology Of CancerHealth DisparitiesCancer IncidenceCancer RegistrationCancer Risk Factors	2006	3.4K
MicroRNAs: Processing, Maturation, Target Recognition and Regulatory Functions. Girish C. Shukla, Jagjit Singh, Sailen Barik PubMed Transcriptional RegulationSystems BiologyDevelopmental BiologyMirna WorldGenetics	2011	782
Patterns of Cancer Incidence, Mortality, and Prevalence Across Five Continents: Defining Priorities to Reduce Cancer Disparities in Different Geographic Regions of the World Farin Kamangar, Graça M. Dores, William F. Anderson Journal of Clinical Oncology Epidemiology Of CancerHealth DisparitiesCancer IncidenceCancer RegistrationCancer Risk Factors	2023	326
Ftx non coding RNA-derived miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular carcinoma Zhikui Liu, Changwei Dou, Bowen Yao, Oncotarget	2016	127
Immunohistochemical expression of the c-kit proto-oncogene product in human malignant and non-malignant breast tissues X Chui, H Egami, Junji Yamashita, British Journal of Cancer Breast OncologyOncogenic AgentC-kit Proto-oncogene ProductImmunologyImmunohistochemical Expression	1996	124
Dynamic intracellular survivin in oral squamous cell carcinoma: underlying molecular mechanism and potential as an early prognostic marker Knut Engels, Dirk Metzler, C Simf, The Journal of Pathology PathologyCancer BiologyTumor BiologyUnderlying Molecular MechanismOral Cancer	2007	115
MiRNA-203 suppresses cell proliferation, migration and invasion in colorectal cancer via targeting of EIF5A2 Biao Deng, Bin Wang, Jiaqing Fang, Scientific Reports	2016	104

Page 1