Effects of early enteral bovine colostrum supplementation on intestinal permeability in critically ill patients: A randomized, double-blind, placebo-controlled study

APACHE II

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1985 · 13.7K citations

Medicine, Internal Medicine, Clinical Classification Systems +16

APACHE II-A Severity of Disease Classification System

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1986 · 13.4K citations

Health Professions, Biostatistics, Clinical Classification Systems +12

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure

Jean‐Louis Vincent, Rui P. Moreno, Jukka Takala et al. · Intensive Care Medicine · 1996 · 11.6K citations

Veterinary Medicine, Internal Medicine, Critical Care Medicine +12

Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient

Stephen A. McClave, Beth Taylor, Robert G. Martindale et al. · Journal of Parenteral and Enteral Nutrition · 2016 · 3.9K citations · Full text

Agriculture, Nutrition, Nutritional Sciences +12

Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool

Daren K. Heyland, Rupinder Dhaliwal, Xuran Jiang et al. · Critical Care · 2011 · 851 citations · Full text

Agriculture, Nutrition, Nutritional Sciences +17