Concepedia

Repeated mutKRAS ctDNA measurements represent a novel and promising tool for early response prediction and therapy monitoring in advanced pancreatic cancer

Stephan Krüger, Volker Heinemann, C. M. D. Ross, Frank Diehl, D. Nagel, Steffen Ormanns, Sibylle Liebmann, I. Prinz-Bravin, C. Benedikt Westphalen, Michael Haas,

Annals of Oncology · 2018 · 157 citations · 15 references

DOIFull text

Open access

Abstract

mutKRAS ctDNA kinetics appear to be a powerful and highly specific tool in early response prediction and therapy monitoring of advanced PC patients receiving chemotherapy.

References

15

Pancreatic Adenocarcinoma, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology

Margaret A. Tempero, Mokenge P. Malafa, Mahmoud M. Al-Hawary et al. · Journal of the National Comprehensive Cancer Network · 2017 · 1K citations

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Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers

Joshua D. Cohen, Ammar A. Javed, Christopher J. Thoburn et al. · Proceedings of the National Academy of Sciences · 2017 · 557 citations · Full text

BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions

Frank Diehl, Meng Li, Yiping He et al. · Nature Methods · 2006 · 489 citations

, , +2

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

Mark Sausen, Jillian Phallen, Vilmos Adleff et al. · Nature Communications · 2015 · 477 citations · Full text

Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas

Oliver A. Zill, Claire Greene, Dragan Sebisanovic et al. · Cancer Discovery · 2015 · 276 citations · Full text