Concepedia

Functional abnormalities in induced Pluripotent Stem Cell-derived cardiomyocytes generated from titin-mutated patients with dilated cardiomyopathy

Revital Schick, Lucy N. Mekies, Yuval Shemer, Binyamin Eisen, Tova Hallas, Ronen Ben Jehuda, Meital Ben-Ari, Ágnes Szántai, Lubna Willi, Rita Shulman,

PLoS ONE · 2018 · 54 citations · 37 references

Open access

Abstract

These findings show that the mutated cardiomyocytes from DCM patients recapitulate abnormalities of the inherited cardiomyopathies, expressed as blunted inotropic response.

References

37

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

Jürgen Cox, Matthias Mann · Nature Biotechnology · 2008 · 15.3K citations

Biochemistry, Identification Rates, Natural Sciences +10

The Perseus computational platform for comprehensive analysis of (prote)omics data

Stefka Tyanova, Tikira Temu, Pavel Sinitcyn et al. · Nature Methods · 2016 · 8.5K citations

Engineering, Medicine, Omics Integration +10

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

Jürgen Cox, Nadin Neuhauser, Annette Michalski et al. · Journal of Proteome Research · 2011 · 5.7K citations

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

Nils A. Kulak, Garwin Pichler, Igor Paron et al. · Nature Methods · 2014 · 1.8K citations

Bioinformatics, Proteomic Technology, Functional Genomics +15

Truncations of Titin Causing Dilated Cardiomyopathy

Daniel S. Herman, Lien Lam, Matthew R.G. Taylor et al. · New England Journal of Medicine · 2012 · 1.4K citations · Full text