Concepedia

Significance of IgG4-positive cells in severe eosinophilic chronic rhinosinusitis

Takahisa Koyama, Shin Kariya, Yasuharu Sato, Yuka Gion, Takaya Higaki, Takenori Haruna, Tazuko Fujiwara, Akira Minoura, Soshi Takao, Yorihisa Orita,

Allergology International · 2018 · 37 citations · 27 references

DOIFull text

Open access

Abstract

Our results suggest that the local expression of IgG4 on cells may be used as a biomarker that reflects the pathophysiology of CRS, including the post-operative course.

References

27

European Position Paper on Rhinosinusitis and Nasal Polyps 2020

W.J. Fokkens, Valerie J. Lund, C. Hopkins et al. · Rhinology Journal · 2020 · 5.4K citations · Full text

Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers

Peter Tomassen, Griet Vandeplas, Thibaut Van Zele et al. · Journal of Allergy and Clinical Immunology · 2016 · 1.1K citations · Full text

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Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

Marijn van der Neut Kolfschoten, Janine Schuurman, Mario Losen et al. · Science · 2007 · 957 citations

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Novel scoring system and algorithm for classifying chronic rhinosinusitis: the <scp>JESREC</scp> Study

T Tokunaga, Masafumi Sakashita, Daiya Asaka et al. · Allergy · 2015 · 642 citations · Full text

Diversity of TH cytokine profiles in patients with chronic rhinosinusitis: A multicenter study in Europe, Asia, and Oceania

Xiangdong Wang, Nan Zhang, Mingyu Bo et al. · Journal of Allergy and Clinical Immunology · 2016 · 599 citations · Full text