Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by <i>SLC29A4</i> ) and Organic Cation Transporter 1 (OCT1) (Encoded by <i>SLC22A1</i> ) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study - Concepedia

Concepedia

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Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by <i>SLC29A4</i> ) and Organic Cation Transporter 1 (OCT1) (Encoded by <i>SLC22A1</i> ) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study

DOI Full Paper Access

61

Citations

40

References

2019

Year

Adem Y. Dawed, Kaixin Zhou, Nienke van Leeuwen, Anubha Mahajan, Neil Robertson, Robert W. Koivula, Petra J. M. Elders, Simone P. Rauh, Angus G. Jones, Reinhard W. Holl,

Abstract

These results suggest that intestinal metformin transporters and concomitant medications play an important role in the gastrointestinal adverse effects of metformin.

References

	Year	Citations

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