Dynamics of a diffusive virus model with general incidence function, cell-to-cell transmission and time delay

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On the definition and the computation of the basic reproduction ratio R0 in models for infectious diseases in heterogeneous populations.

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

David D. Ho, Avidan U. Neumann, Alan S. Perelson et al. · Nature · 1995 · 4.3K citations

Life Sciences, Immunology, Infectious Diseases +14

HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

Alan S. Perelson, Avidan U. Neumann, Martin Markowitz et al. · Science · 1996 · 3.5K citations

Life Sciences, Infectious Diseases, Microbiology +16

Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy

Alex Sigal, Jocelyn T. Kim, Alejandro B. Balazs et al. · Nature · 2011 · 537 citations

Life Sciences, Infectious Diseases, Microbiology +16