On the definition and the computation of the basic reproduction ratio R0 in models for infectious diseases in heterogeneous populations.
Data Archiving and Networked Services (DANS) · 1990 · 5.1K citations · 13 references
The expected number of secondary cases produced by a typical infected individual during its entire period of infectiousness in a completely susceptible population is mathematically defined as the dominant eigenvalue of a positive linear operator. It is shown that in certain special cases one can easily compute or estimate this eigenvalue. Several examples involving various structuring variables like age, sexual disposition and activity are presented.
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Modeling and analyzing HIV transmission: the effect of contact patterns
John A. Jacquez, Carl G. Simon, James S. Koopman et al. · Mathematical Biosciences · 1988
402 citations
Herbert W. Hethcote, James W. Van Ark · Mathematical Biosciences · 1987
VaccinationInfectious Disease EpidemiologyInfectious Disease Modelling+11
283 citations
Using mathematical models to understand the AIDS epidemic
James M. Hyman, E. Ann Stanley · Mathematical Biosciences · 1988
253 citations
Heterogeneity in disease-transmission modeling
Annett Nold · Mathematical Biosciences · 1980
Disease-transmission ModelingDisease ModelsInfectious Disease Modeling+5
241 citations
The growth and composition of branching populations
Peter Jagers, Olle Nerman · Advances in Applied Probability · 1984
162 citations