Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Carles Cantó, Zachary Gerhart‐Hines, Jérôme N. Feige et al. · Nature · 2009 · 3.1K citations · Full text

Energy Metabolism, Signal Transduction, Biochemistry +14

The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver

DH Williamson, P. Kay Lund, HA Krebs · Biochemical Journal · 1967 · 1.9K citations · Full text

Molecular Biology, Free Nicotinamide-adenine Dinucleotide, Redox Biology +16

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

Kıvanç Birsoy, Walter W. Chen, Elizaveta Freinkman et al. · Cell · 2015 · 1.4K citations · Full text

Biosynthesis, Essential Role, Biochemistry +9

Genetically encoded fluorescent indicator for intracellular hydrogen peroxide

Vsevolod V. Belousov, Arkady F. Fradkov, Konstantin A. Lukyanov et al. · Nature Methods · 2006 · 1.2K citations

Redox Signaling, Biochemistry, Reporter Gene Assay +8

Quantitative flux analysis reveals folate-dependent NADPH production

Jing Fan, Jiangbin Ye, Jurre J. Kamphorst et al. · Nature · 2014 · 1.1K citations · Full text

Quantitative Flux Analysis, Biochemistry, Bioenergetics +6