Journal of Biological Chemistry · 2018 · 22 citations · 35 references
Life SciencesCell BiologyMolecular BiologyCell SignalingGene ExpressionTranscriptional RegulationProtein DegradationE3 Ubiquitin Ligase Substrate RecognitionRegulation By E3 Ubiquitin LigasesUbiquitin-binding DomainsUbiquitin-mediated ProteolysisWw Domains
Notch) ubiquitination. Our study demonstrates an evolutionarily conservative mechanism governing the regulation and activation of some Nedd4 family E3 ligases. Our results also suggest a dual regulatory mechanism for specific Notch down-regulation via dNdfip-Su(dx)-mediated Notch ubiquitination.
35
The EMBL-EBI bioinformatics web and programmatic tools framework
Weizhong Li, Andrew Cowley, Mahmut Uludağ et al. · Nucleic Acids Research · 2015 · 1.1K citations · Full text
Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain
Silke Wiesner, Abiodun A. Ogunjimi, Hongrui Wang et al. · Cell · 2007 · 281 citations · Full text