Chemical Communications · 2018 · 37 citations · 33 references
Natural SciencesChemistryMedicinal ChemistryCatalysisOrganic ChemistryCatalyst DesignCatalyst PreparationCatalyst SynthesisCatalytic MaterialsCatalytic MechanismsRetrosynthetic AnalysisCatalytic Reaction MechanismsChemoselective CatalysisChemoselective CouplingChemoselective SynthesisEpoxidationEpoxide FormationKetonesMild Reaction Conditions
The development of the highly active pincer-type rhodium catalyst 2 for the nucleophilic Meinwald rearrangement of functionalised terminal epoxides into methyl ketones under mild conditions is presented. An excellent regio- and chemoselectivity is obtained for the first time for aryl oxiranes.
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