Antimicrobial Agents and Chemotherapy · 2018 · 26 citations · 24 references
MedicineMicrobiologyPharmacologyAntimicrobial PharmacologyMedical MicrobiologyMycologyAntifungal AgentsAntifungal PharmacologyAntifungal TherapyFungal InfectionsOral Fungal InfectionsOral Fungal MicrobiologyAntifungal TreatmentsItraconazole TherapyNew Antifungal AgentsNovel Antifungal Drug DevelopmentOnychomycosis TreatmentTavaborole TherapyTopical Antifungal AgentsTopical Antifungals
The in vitro activity of tavaborole, an FDA-approved antifungal drug, was compared to that of four antifungal agents against 170 clinical fungal isolates originating from patients with onychomycosis. Tavaborole had low activity against all isolates compared to itraconazole, terbinafine, and fluconazole, the principal choices for treatment of onychomycosis.
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An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site
Fernando Rock, Weimin Mao, A. Yaremchuk et al. · Science · 2007 · 631 citations · Full text
Onychomycosis: Current trends in diagnosis and treatment.
Dyanne P. Westerberg, Michael J Voyack · PubMed · 2013 · 237 citations
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Fungal Nail Infections (Onychomycosis): A Never-Ending Story?
Mahmoud A. Ghannoum, N. Isham · PLoS Pathogens · 2014 · 125 citations · Full text
Medicine, Dermatology, Microbiology +14