Bioorganic & Medicinal Chemistry · 2018 · 13 citations · 54 references
MedicineMedicinal ChemistryPharmacologyChemotherapyDrug DiscoveryOrganic ChemistryEnzyme InhibitionHeterocyclic ChemistryStructure-activity Relationship AnalysisTopoisomerase InhibitorsCatalytic Topoisomerase InhibitionChemical Structure-activity RelationshipsTopoisomerase I InhibitorsTopoisomerase Ii FunctionTopoisomerase Ii Inhibitors
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Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II
K M Tewey, Thomas C. Rowe, Liu Yang et al. · Science · 1984 · 1.5K citations
Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA
Matthew R. Redinbo, Lance Stewart, Peter Kühn et al. · Science · 1998 · 878 citations