An integrated automated multispectral imaging technique that simultaneously detects and quantitates viral RNA and immune cell protein markers in fixed sections from Epstein-Barr virus-related tumours

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 ⁺ T lymphocytes are prognostic factors of human ovarian cancer

Junzo Hamanishi, Masaki Mandai, Masashi Iwasaki et al. · Proceedings of the National Academy of Sciences · 2007 · 1.4K citations · Full text

Medicine, Immunology, Oncology +17

PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma

Paul Nghiem, Shailender Bhatia, Evan J. Lipson et al. · New England Journal of Medicine · 2016 · 1.2K citations · Full text

Medicine, Dermatology, Oncology +17

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis

Sara Lovisa, Valerie S. LeBleu, Björn Tampe et al. · Nature Medicine · 2015 · 982 citations · Full text

Medicine, Cell Biology, Nephrology +17

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis

Bernhard Mlecnik, Gabriela Bindea, Amos Kirilovsky et al. · Science Translational Medicine · 2016 · 474 citations · Full text

Medicine, Cancer Biology, Immunology +13

Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma

Marta Garnelo, Alex Y. Tan, Zhisheng Her et al. · Gut · 2015 · 469 citations · Full text

Medicine, Immunology, Oncology +17