Silymarin prevents acetaminophen-induced hepatotoxicity via up-regulation of the glutathione conjugation capacity in mice

Glutathione S-Transferases

William H. Habig, M. Pabst, William B. Jakoby · Journal of Biological Chemistry · 1974 · 18.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

T. Nash · Biochemical Journal · 1953 · 4.4K citations · Full text

Natural Sciences, Biochemistry, Chemistry +7

Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics

Chris J. Patten, Paul E. Thomas, Robert L. Guy et al. · Chemical Research in Toxicology · 1993 · 413 citations

Medicine, Pharmacology, Toxicology +17

Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a.

Dennis R. Koop · Molecular Pharmacology · 1986 · 342 citations

Medicine, Biochemistry, Pharmacology +17

Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: the protective effect of allopurinol.

Hartmut Jaeschke · Journal of Pharmacology and Experimental Therapeutics · 1990 · 334 citations

Veterinary Medicine, Pharmacology, Toxicology +17