Concepedia

Chemotherapy-induced niche perturbs hematopoietic reconstitution in B-cell acute lymphoblastic leukemia

Chao Tang, Minghao Li, Yali Chen, Huiying Sun, Shengli Liu, Wei‐Wei Zheng, Meng‐Yi Zhang, Hui Li, Wei Fu, Wenjun Zhang,

Journal of Experimental & Clinical Cancer Research · 2018 · 24 citations · 22 references

DOIFull text

Open access

Abstract

Chemotherapy-induced BM niche perturbs the hematopoietic reconstitution of HSCs by increasing intracellular ROS level and inducing cell apoptosis.

References

22

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

Mark J. Kiel, Ömer Yılmaz, Toshihide Iwashita et al. · Cell · 2005 · 3.1K citations · Full text

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Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

Stuart H. Orkin, Leonard I. Zon · Cell · 2008 · 2.5K citations · Full text

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Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche

Fumio Arai, Atsushi Hirao, Masako Ohmura et al. · Cell · 2004 · 1.9K citations · Full text

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Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

Anne Wilson, Elisa Laurenti, Gabriela Oser et al. · Cell · 2008 · 1.8K citations

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Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature Medicine · 2006 · 1.3K citations

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