Concepedia

FOS, a Critical Downstream Mediator of PGR and EGF Signaling Necessary for Ovulatory Prostaglandins in the Human Ovary

Yohan Choi, Katherine L. Rosewell, Mats Brännström, James W. Akin, Thomas E. Curry, Misung Jo

The Journal of Clinical Endocrinology & Metabolism · 2018 · 80 citations · 35 references

DOIFull text

Open access

Abstract

The increase of FOS/activator protein 1 in human periovulatory follicles after hCG administration is mediated by collaborative actions of PGR and EGF signaling and critical for the upregulated expression of key ovulatory genes required for the rise in ovulatory PG in human granulosa cells.

References

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