Concepedia

Discovery of 1-((6-Aminopyridin-3-yl)Methyl)-3-(4-Bromophenyl)Urea as a Potent, Irreversible Myeloperoxidase Inhibitor

Martı́n L. Marro, Andrew W. Patterson, Lac Lee, Aimee Reynolds, Xianglin Ren, Laura Axford, Anup Patnaik, Micah Hollis‐Symynkywicz, Nigel Casson, Dominique Custeau,

Journal of Pharmacology and Experimental Therapeutics · 2018 · 13 citations · 26 references

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26

Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists.

Robert A. Copeland · PubMed · 2005 · 1.1K citations

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Myeloperoxidase, a Leukocyte-Derived Vascular NO Oxidase

Jason P. Eiserich, Stephan Baldus, Marie-Luise Brennan et al. · Science · 2002 · 683 citations

, , +17

Hypochlorous Acid, a Macrophage Product, Induces Endothelial Apoptosis and Tissue Factor Expression

Seigo Sugiyama, Kiyotaka Kugiyama, Masanori Aikawa et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2004 · 417 citations · Full text

, , +12

Myeloperoxidase of the leucocyte of normal human blood. I. Content and localization

Julius Schultz, Kenneth Kaminker · Archives of Biochemistry and Biophysics · 1962 · 405 citations

, , +4

Increased atherosclerosis in myeloperoxidase-deficient mice

Marie‐Luise Brennan, Melissa M. Anderson, Diana M. Shih et al. · Journal of Clinical Investigation · 2001 · 325 citations · Full text

, , +17