Cellular and Molecular Biology · 2018 · 17 citations · 0 references
MedicineOncologyPharmacologyCancer PharmacologyCarcinogenesisMolecular OncologyCancer Cell SignalingMalignant NeoplasmsNoncoding Rna In CancerOncogenic Signaling PathwaysSignal Transduction In CancerKnowledge GapsMicrorna Function In CancerMicrorna In CancerMicrorna ModulationMicrorna Regulation In CancerMicrorna-mediated Pathway RegulationOncogenic Signaling NetworksSignal Transduction Cascades
Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.