Concepedia

The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome

Maciej Sałaga, Agata Binienda, Ritesh Tichkule, Ganesh A. Thakur, Alexandros Makriyannis, Martin Storr, Jakub Fichna

European Journal of Pharmacology · 2018 · 14 citations · 23 references

DOI

Concepts

References

23

Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Enhances Heterodimer Formation: A Mechanism for Receptor Cross-Talk?

Christopher S. Kearn, Katherine G. Blake-Palmer, Emma Daniel et al. · Molecular Pharmacology · 2005 · 353 citations

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<i>μ</i> opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis

Carl Rios, Ivone Gomes, Lakshmi A. Devi · British Journal of Pharmacology · 2006 · 315 citations · Full text

, , +16

Orexin-1 Receptor-Cannabinoid CB1 Receptor Heterodimerization Results in Both Ligand-dependent and -independent Coordinated Alterations of Receptor Localization and Function

James Ellis, John D. Pediani, Meritxell Canals et al. · Journal of Biological Chemistry · 2006 · 220 citations · Full text

, , +16

Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation

Atheer Zgair, Jong Bong Lee, Jonathan C.M. Wong et al. · Scientific Reports · 2017 · 127 citations · Full text

, , +8

Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients With Nonconstipated Irritable Bowel Syndrome

Banny S. Wong, Michael Camilleri, Irene Busciglio et al. · Gastroenterology · 2011 · 99 citations · Full text

, , +11