TGF‐β1 and connexin‐43 expression in neurogenic bladder from rats with sacral spinal cord injury

Abstract

This study indicates that voiding dysfunction is related to the decreased CX43 function in detrusor from NB. TGF-β1/Smad3 signaling might be involved in the down-regulation of CX43 in SCI rats. Early regulation of CX43 might be beneficial to patients with voiding dysfunction.