Concepedia

Peptidoglycan recycling contributes to intrinsic resistance to fosfomycin in Acinetobacter baumannii

María Luisa Gil-Marqués, Patricia Moreno-Martínez, Coloma Costas, Jerónimo Pachón, Jesús Blázquez, Michael J. McConnell

Journal of Antimicrobial Chemotherapy · 2018 · 26 citations · 31 references

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Abstract

This study demonstrates that AmpD and AnmK of the peptidoglycan recycling pathway contribute to intrinsic fosfomycin resistance in A. baumannii, indicating that inhibitors of these enzymes could be used in combination with fosfomycin as a novel treatment approach for MDR A. baumannii.

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