Concepedia

Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling

Dominic De Nardo, Katherine R. Balka, Yamel Cardona Gloria, Vikram R. Rao, Eicke Latz, Seth L. Masters

Journal of Biological Chemistry · 2018 · 140 citations · 43 references

DOIFull text

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Concepts

References

43

Oncogenically active MYD88 mutations in human lymphoma

Vu N. Ngo, Ryan M. Young, Roland Schmitz et al. · Nature · 2010 · 1.5K citations · Full text

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Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

Horst von Bernuth, Capucine Pïcard, Zhongbo Jin et al. · Science · 2008 · 1.3K citations · Full text

, , +14

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

Jonathan C. Kagan, Tian Su, Tiffany Horng et al. · Nature Immunology · 2008 · 1.2K citations · Full text

, , +14

MyD88: An Adapter That Recruits IRAK to the IL-1 Receptor Complex

Holger Wesche, William J. Henzel, Wendy Shillinglaw et al. · Immunity · 1997 · 1.1K citations · Full text

, , +5

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

Su‐Chang Lin, Yu-Chih Lo, Hao Wu · Nature · 2010 · 1K citations · Full text

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