Bead-extraction and heat-dissociation (BEHD): A novel way to overcome drug and matrix interference in immunogenicity testing

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Nicole Casadevall, J Nataf, B Viron et al. · New England Journal of Medicine · 2002 · 1.2K citations

Medicine, Hematology, Immunology +11

Analysis of Messy Data, Volume I: Designed Experiments

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Public Health, Data Science, Experimental Design +2

Recommendations for the design and optimization of immunoassays used in the detection of host antibodies against biotechnology products

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Life Sciences, Biotechnology, Immunology +13

Detection of antibodies against therapeutic proteins in the presence of residual therapeutic protein using a solid-phase extraction with acid dissociation (SPEAD) sample treatment prior to ELISA

Holly W. Smith, Anthony Butterfield, Deqin Sun · Regulatory Toxicology and Pharmacology · 2007 · 130 citations

Life Sciences, Biochemistry, Pharmaceutics +15

Detection of neutralizing anti-therapeutic protein antibodies in serum or plasma samples containing high levels of the therapeutic protein

James A. Lofgren, Iwona Wala, Eugen Koren et al. · Journal of Immunological Methods · 2005 · 81 citations

Life Sciences, Biochemistry, Immunology +15